“The drug for tooth growth will undergo clinical trials at Kyoto University“- reports the Japanese portal “The Asahi Shimbun”. The cited scientists say that The world’s first such trials in humans will begin in September.
A team at the Kitano Hospital, a medical research institute in Osaka, believes The drug should be brought to market by 2030, which can be used to treat people with congenital endulism, a condition in which they are born with fewer teeth than normal. The condition, which is often inherited, affects about one in 1,000 people.
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Born without six or more teeth, these patients have difficulty eating and developing jaws properly. In adulthood, they often rely on dentures or implants. No cure has yet been found for this.
“The research team, led by Katsu Takahashi, head of the Department of Dentistry and Oral Surgery at Kitano Hospital, focused their research on USAG-1, a molecule that inhibits the activity of bone-forming proteins. The team developed The drug suppresses the effects of USAG-1, which is why rats and beagles grow teeth“writes the Japanese portal.
In a clinical trial that will last until August 2025.Healthy adults receive Drug injectionTo check if they have any health problems.
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After confirming the drug’s safety, the team plans to move to the next phase of testing in children ages 2 to 7 who have four or more missing teeth.
Scientists say the drug may also help patients who have lost teeth due to gum disease or trauma. They also hope the drug could be a third option that stands apart from existing dentures and implants.